Sean Dickson’s 57th-minute penalty earned us a share of the spoils at Galabank after Smart Osadolor had given the home side the lead immediately after half-time.
Kevin McKinlay was sent off for what was deemed to be a reckless challenge on Rabin Omar just after we equalised and Annan had Peter Watson red carded for kicking out at Craig Comrie 10 minutes from time.
Binos boss Stuart McLaren made two changes to the team beaten 1-0 by Clyde, with skipper Ross McMillan and Kevin McKinlay replacing Mark Staunton (suspended) and Ross Forsyth, who dropped to the bench.
Ex-Albion manager Greig McDonald was among the subs for Jim Chapman’s team, who kicked off their Ladbrokes League 2 campaign with a 1-0 win at Queen’s Park.
Annan had more of the chances and will feel they should have had won but we showed good spirit with the numerical disadvantage to get our season up and running.
Peter Weatherson missed the best opportunity of the first half when he failed to beat Chris Smith from close range and the hosts had a penalty appeal waved away when a cross from the right struck Comrie on the arm.
We came close to a goal when Dickson smacked a shot against the top of the bar from 30 yards but it was Annan who broke the deadlock 19 seconds after the break.
The impressive Osadolor was allowed to run unchecked into the box and, despite losing possession, was able to slam the ball into the net after we twice failed to clear.
Josh Todd missed a simple chance to double the lead but we hit back when Craig Beattie went down under a challenge from Steven Sloan and referee Nick Walsh pointed to the spot.
It looked a soft award but a number of those decisions have gone against us in recent weeks and Dickson found the bottom corner from 12 yards.
McKinlay then saw red and assistant manager Martyn Corrigan was sent to the stand for protesting but the video highlights appear to show that it was the correct call.
Watson was sent packing for an off-the-ball incident with Comrie as it ended all square on our first visit to Galabank since the 5-3 play-off win in May 2014.
Annan Athletic: Hart, Black, Swinglehurst, McNiff, P Watson, Sloan (McColm 76), Omar (Park 88), Flynn, Weatherson, Todd, Osadolor.
Subs (not used): McStay, J Watson, McDonald, Norman, Currie (GK).
Scorer: Osadolor 46
Stirling Albion: C Smith, Hamilton, McKinlay, Robertson, McGeachie, McMillan, Johnston (Doris 82), Comrie, Beattie (Forsyth 62), McGovern, Dickson (McKenzie 88).
Subs (not used): R Smith, Cunningham, Kouider-Aissa, Binnie (GK).
Scorer: Dickson pen 57
Referee: Nick Walsh