Jordan White scored his 10th goal of the season as we came from behind to record a deserved victory and extend our unbeaten run to four games.
Former Partick midfielder Scott Chaplain gave Annan the lead but Graham Weir equalised before the break and White grabbed the winner from close range five minutes into the second period.
Albion carved out several good chances and should have won by a greater margin as we moved to within three points of Clyde, who we face at Forthbank on Saturday seeking revenge for two previous defeats to the Bully Wee.
Binos boss Greig McDonald drafted in Gary Thom for the suspended Brian Allison and there was a first league start for 17-year-old striker Sandy Cunningham, who did very well during the hour he was on the pitch.
Annan, without a win in four matches, went ahead in 15 minutes when poor defending allowed the unmarked Chaplain to drill a low shot beyond David Crawford.
White had the ball in the net 60 seconds later but the offside flag had already gone up but we drew level in 21 minutes when Cunningham forced a save from Alex Mitchell and Weir stroked home the rebound for his fifth goal of the season.
Thom had a header cleared off the line and Mitchell superbly kept out a White header from Phil Johnston’s cross but a second goal eventually arrived soon after the restart when Thom found White, who controlled the ball and beat Mitchell.
White and sub Scott Davidson both came close to increasing our lead and it was only in the closing stages that Annan threatened – Crawford saved a Michael Daly header in the last minute but an equaliser would have been cruel.
Stirling Albion: Crawford, McCunnie, Forsyth, McClune, Bishop, Thom, Weir (McAnespie 90), Ferry, White, Cunningham (Davidson 62), Johnston (Flood 83).
Subs (not used): Day, Filler (GK).
Scorers: Weir 21, White 50
Annan Athletic: Mitchell, Sloan, McGowan, Trialist, Swinglehurst (Jardine 75), McNiff (McKechnie 71), Orsi, Chaplain, Daly, Hopkirk, Monaghan (Love 62).
Subs (not used): Hawke, Summersgill (GK).
Scorer: Chaplain 15
Referee: Alan Muir